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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP1
All Species:
20
Human Site:
T70
Identified Species:
44
UniProt:
Q13541
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13541
NP_004086.1
118
12580
T70
R
N
S
P
V
T
K
T
P
P
R
D
L
P
T
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
T83
C
N
S
P
M
V
Q
T
P
P
C
H
L
P
N
Rhesus Macaque
Macaca mulatta
XP_001091933
141
14878
T70
R
N
S
P
V
T
K
T
P
P
K
D
L
P
A
Dog
Lupus familis
XP_549448
118
12523
T70
R
N
S
P
V
T
K
T
P
P
R
D
L
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60876
117
12306
T69
R
N
S
P
V
A
K
T
P
P
K
D
L
P
A
Rat
Rattus norvegicus
Q62622
117
12385
T69
R
N
S
P
V
A
K
T
P
P
K
D
L
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514570
67
7606
K20
C
R
N
S
P
V
A
K
T
P
P
R
D
L
P
Chicken
Gallus gallus
XP_424384
116
12481
A69
E
C
R
N
S
P
V
A
K
T
P
P
S
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
R65
C
R
N
S
P
I
A
R
T
P
P
C
C
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120078
115
12648
R68
L
R
N
S
P
I
S
R
T
P
P
R
N
M
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
P65
L
L
N
M
R
N
S
P
L
S
Q
T
P
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
75.8
94.9
N.A.
90.6
92.3
N.A.
44.9
66
N.A.
56.7
N.A.
N.A.
47.4
N.A.
52.5
Protein Similarity:
100
59.4
80.1
97.4
N.A.
94
95.7
N.A.
49.1
76.2
N.A.
67.8
N.A.
N.A.
65.2
N.A.
66.1
P-Site Identity:
100
53.3
86.6
100
N.A.
80
86.6
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
66.6
93.3
100
N.A.
86.6
93.3
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
19
10
0
0
0
0
0
0
19
% A
% Cys:
28
10
0
0
0
0
0
0
0
0
10
10
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
46
10
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
46
10
10
0
28
0
0
0
10
% K
% Leu:
19
10
0
0
0
0
0
0
10
0
0
0
55
19
10
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
55
37
10
0
10
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
55
28
10
0
10
55
82
37
10
10
64
28
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
46
28
10
0
10
0
0
19
0
0
19
19
0
0
0
% R
% Ser:
0
0
55
28
10
0
19
0
0
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
28
0
55
28
10
0
10
0
0
28
% T
% Val:
0
0
0
0
46
19
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _